Cargando…
Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities
BACKGROUND: Previous studies assessing esophageal motility in chronic renal failure (CRF) patients had no consistency in their findings. These studies evaluated esophageal contractility in response to dry/water swallows. Our aim was to reassess esophageal motility in CRF patients to better define it...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139754/ https://www.ncbi.nlm.nih.gov/pubmed/27942314 http://dx.doi.org/10.4021/gr300w |
_version_ | 1782472300645318656 |
---|---|
author | Kuwahara, Clovis Massato Rosa-e-Silva, Lucilene Mocelin, Altair Jacob Zebian, Miriam Pontes, Rose Meire Albuquerque Dantas, Roberto Oliveira |
author_facet | Kuwahara, Clovis Massato Rosa-e-Silva, Lucilene Mocelin, Altair Jacob Zebian, Miriam Pontes, Rose Meire Albuquerque Dantas, Roberto Oliveira |
author_sort | Kuwahara, Clovis Massato |
collection | PubMed |
description | BACKGROUND: Previous studies assessing esophageal motility in chronic renal failure (CRF) patients had no consistency in their findings. These studies evaluated esophageal contractility in response to dry/water swallows. Our aim was to reassess esophageal motility in CRF patients to better define its abnormalities. To unmask minor defects not seen in conventional dry/water manometry we also evaluated esophageal contractility in response to a highly viscous substance. METHODS: Fifteen controls and nine asymptomatic CRF patients underwent esophageal manometry with dry swallows, swallows of 5 mL of water (1 centipoise) and 5 mL of sugar cane syrup (24500 centipoise). CRF patients were compared with controls for esophageal motility parameters, considering each type of swallow (dry/water/syrup). RESULTS: CRF patients had: tendency for higher lower esophageal sphincter (LES) resting pressure (P = 0.09); shorter LES relaxation duration after dry/water/syrup swallows (P = 0.0001, P < 0.0001, P = 0.0001, respectively); higher amplitude of proximal contractions after dry/water/syrup swallows (P = 0.008, P = 0.01, P = 0.04); tendency for longer duration of distal contractions after dry/water/syrup swallows (P = 0.07, P = 0.04, P = 0.09); lower velocity of distal contractions after dry/water/syrup swallows (P = 0.006, P = 0.09, P = 0.02); and higher incidence of multi-peaked contractions after dry/water/syrup swallows (P = 0.03, P = 0.0001, P < 0.0001). CONCLUSIONS: Esophageal motility dysfunction can be a sub-clinical manifestation in CRF patients. Data also showed that swallows of a highly viscous liquid did not help to detect minor esophageal dysmotility in these patients. |
format | Online Article Text |
id | pubmed-5139754 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-51397542016-12-09 Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities Kuwahara, Clovis Massato Rosa-e-Silva, Lucilene Mocelin, Altair Jacob Zebian, Miriam Pontes, Rose Meire Albuquerque Dantas, Roberto Oliveira Gastroenterology Res Original Article BACKGROUND: Previous studies assessing esophageal motility in chronic renal failure (CRF) patients had no consistency in their findings. These studies evaluated esophageal contractility in response to dry/water swallows. Our aim was to reassess esophageal motility in CRF patients to better define its abnormalities. To unmask minor defects not seen in conventional dry/water manometry we also evaluated esophageal contractility in response to a highly viscous substance. METHODS: Fifteen controls and nine asymptomatic CRF patients underwent esophageal manometry with dry swallows, swallows of 5 mL of water (1 centipoise) and 5 mL of sugar cane syrup (24500 centipoise). CRF patients were compared with controls for esophageal motility parameters, considering each type of swallow (dry/water/syrup). RESULTS: CRF patients had: tendency for higher lower esophageal sphincter (LES) resting pressure (P = 0.09); shorter LES relaxation duration after dry/water/syrup swallows (P = 0.0001, P < 0.0001, P = 0.0001, respectively); higher amplitude of proximal contractions after dry/water/syrup swallows (P = 0.008, P = 0.01, P = 0.04); tendency for longer duration of distal contractions after dry/water/syrup swallows (P = 0.07, P = 0.04, P = 0.09); lower velocity of distal contractions after dry/water/syrup swallows (P = 0.006, P = 0.09, P = 0.02); and higher incidence of multi-peaked contractions after dry/water/syrup swallows (P = 0.03, P = 0.0001, P < 0.0001). CONCLUSIONS: Esophageal motility dysfunction can be a sub-clinical manifestation in CRF patients. Data also showed that swallows of a highly viscous liquid did not help to detect minor esophageal dysmotility in these patients. Elmer Press 2011-04 2011-03-20 /pmc/articles/PMC5139754/ /pubmed/27942314 http://dx.doi.org/10.4021/gr300w Text en Copyright 2011, Kuwahara et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kuwahara, Clovis Massato Rosa-e-Silva, Lucilene Mocelin, Altair Jacob Zebian, Miriam Pontes, Rose Meire Albuquerque Dantas, Roberto Oliveira Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities |
title | Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities |
title_full | Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities |
title_fullStr | Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities |
title_full_unstemmed | Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities |
title_short | Esophageal Dysmotility in Chronic Hemodialysis Patients After Ingestion of Liquids With Different Viscosities |
title_sort | esophageal dysmotility in chronic hemodialysis patients after ingestion of liquids with different viscosities |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139754/ https://www.ncbi.nlm.nih.gov/pubmed/27942314 http://dx.doi.org/10.4021/gr300w |
work_keys_str_mv | AT kuwaharaclovismassato esophagealdysmotilityinchronichemodialysispatientsafteringestionofliquidswithdifferentviscosities AT rosaesilvalucilene esophagealdysmotilityinchronichemodialysispatientsafteringestionofliquidswithdifferentviscosities AT mocelinaltairjacob esophagealdysmotilityinchronichemodialysispatientsafteringestionofliquidswithdifferentviscosities AT zebianmiriam esophagealdysmotilityinchronichemodialysispatientsafteringestionofliquidswithdifferentviscosities AT pontesrosemeirealbuquerque esophagealdysmotilityinchronichemodialysispatientsafteringestionofliquidswithdifferentviscosities AT dantasrobertooliveira esophagealdysmotilityinchronichemodialysispatientsafteringestionofliquidswithdifferentviscosities |