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Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study
BACKGROUND: Lung adenocarcinoma (LUAD) is the most common histologic subtype of lung cancer and has a high risk of distant metastasis at every disease stage. We aimed to characterize the genomic landscape of LUAD and identify mutation signatures associated with tumor progression. METHODS AND FINDING...
Autores principales: | Shi, Jianxin, Hua, Xing, Zhu, Bin, Ravichandran, Sarangan, Wang, Mingyi, Nguyen, Cu, Brodie, Seth A., Palleschi, Alessandro, Alloisio, Marco, Pariscenti, Gianluca, Jones, Kristine, Zhou, Weiyin, Bouk, Aaron J., Boland, Joseph, Hicks, Belynda, Risch, Adam, Bennett, Hunter, Luke, Brian T., Song, Lei, Duan, Jubao, Liu, Pengyuan, Kohno, Takashi, Chen, Qingrong, Meerzaman, Daoud, Marconett, Crystal, Laird-Offringa, Ite, Mills, Ian, Caporaso, Neil E., Gail, Mitchell H., Pesatori, Angela C., Consonni, Dario, Bertazzi, Pier Alberto, Chanock, Stephen J., Landi, Maria Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140047/ https://www.ncbi.nlm.nih.gov/pubmed/27923066 http://dx.doi.org/10.1371/journal.pmed.1002162 |
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