Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential

The aims of this study were to (1) characterize basic electrophysiological elements of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) that correspond to clinical properties such as QT-RR relationship, (2) determine the applicability of QT correction and analysis methods, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamoto, Wataru, Asakura, Keiichi, Ando, Hiroyuki, Taniguchi, Tomohiko, Ojima, Atsuko, Uda, Takaaki, Osada, Tomoharu, Hayashi, Seiji, Kasai, Chieko, Miyamoto, Norimasa, Tashibu, Hiroyuki, Yoshinaga, Takashi, Yamazaki, Daiju, Sugiyama, Atsushi, Kanda, Yasunari, Sawada, Kohei, Sekino, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140066/
https://www.ncbi.nlm.nih.gov/pubmed/27923051
http://dx.doi.org/10.1371/journal.pone.0167348

Ejemplares similares

Ejemplares similares