Cargando…

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

Among various innate immune receptor families, the role of C-type lectin receptors (CLRs) in lung protective immunity against Streptococcus pneumoniae (S. pneumoniae) is not fully defined. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar...

Descripción completa

Detalles Bibliográficos
Autores principales: Behler-Janbeck, Friederike, Takano, Tomotsugu, Maus, Regina, Stolper, Jennifer, Jonigk, Danny, Tort Tarrés, Meritxell, Fuehner, Thomas, Prasse, Antje, Welte, Tobias, Timmer, Mattie S. M., Stocker, Bridget L., Nakanishi, Yoichi, Miyamoto, Tomofumi, Yamasaki, Sho, Maus, Ulrich A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140071/
https://www.ncbi.nlm.nih.gov/pubmed/27923071
http://dx.doi.org/10.1371/journal.ppat.1006038