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C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia
Among various innate immune receptor families, the role of C-type lectin receptors (CLRs) in lung protective immunity against Streptococcus pneumoniae (S. pneumoniae) is not fully defined. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar...
Autores principales: | Behler-Janbeck, Friederike, Takano, Tomotsugu, Maus, Regina, Stolper, Jennifer, Jonigk, Danny, Tort Tarrés, Meritxell, Fuehner, Thomas, Prasse, Antje, Welte, Tobias, Timmer, Mattie S. M., Stocker, Bridget L., Nakanishi, Yoichi, Miyamoto, Tomofumi, Yamasaki, Sho, Maus, Ulrich A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140071/ https://www.ncbi.nlm.nih.gov/pubmed/27923071 http://dx.doi.org/10.1371/journal.ppat.1006038 |
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