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Tumor Suppressor Bromodomain-containing Protein 7 Cooperates with Smads to Promote Transforming Growth Factor-β Responses

Smad proteins are central mediators in the canonical transforming growth factor-β (TGF-β) signaling pathway in mammalian cells. We report here that bromodomain-containing protein 7 (BRD7) functions as a novel transcription coactivator for Smads in TGF-β signaling. BRD7 forms a TGF-β inducible comple...

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Detalles Bibliográficos
Autores principales: Liu, Ting, Zhao, Meiling, Liu, Jinquan, He, Zhou, Zhang, Ye, You, Han, Huang, Jun, Lin, Xia, Feng, Xin-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140778/
https://www.ncbi.nlm.nih.gov/pubmed/27270427
http://dx.doi.org/10.1038/onc.2016.204