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Metabolic rewiring in melanoma

Oncogene-driven metabolic rewiring is an adaptation to low nutrient and oxygen conditions in the tumor microenvironment that enables cancer cells of diverse origin to hyperproliferate. Aerobic glycolysis and enhanced reliance on glutamine utilization are prime examples of such rewiring. However, tis...

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Detalles Bibliográficos
Autores principales: Ratnikov, Boris I., Scott, David A., Osterman, Andrei L., Smith, Jeffrey W., Ronai, Ze’ev A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140782/
https://www.ncbi.nlm.nih.gov/pubmed/27270434
http://dx.doi.org/10.1038/onc.2016.198