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Metabolic rewiring in melanoma
Oncogene-driven metabolic rewiring is an adaptation to low nutrient and oxygen conditions in the tumor microenvironment that enables cancer cells of diverse origin to hyperproliferate. Aerobic glycolysis and enhanced reliance on glutamine utilization are prime examples of such rewiring. However, tis...
Autores principales: | Ratnikov, Boris I., Scott, David A., Osterman, Andrei L., Smith, Jeffrey W., Ronai, Ze’ev A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140782/ https://www.ncbi.nlm.nih.gov/pubmed/27270434 http://dx.doi.org/10.1038/onc.2016.198 |
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