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Succinate/NLRP3 Inflammasome Induces Synovial Fibroblast Activation: Therapeutical Effects of Clematichinenoside AR on Arthritis

Clematichinenoside AR (C-AR) is a triterpene saponin isolated from the root of Clematis manshurica Rupr., which is a herbal medicine used in traditional Chinese medicine for the treatment of arthritis. C-AR exerts anti-inflammatory and immunosuppressive properties, but little is known about its acti...

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Detalles Bibliográficos
Autores principales: Li, Yi, Zheng, Jia-Yi, Liu, Jian-Qun, Yang, Jie, Liu, Yang, Wang, Chen, Ma, Xiao-Nan, Liu, Bao-Lin, Xin, Gui-Zhong, Liu, Li-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141240/
https://www.ncbi.nlm.nih.gov/pubmed/28003810
http://dx.doi.org/10.3389/fimmu.2016.00532