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In silico Screening and Evaluation of the Anticonvulsant Activity of Docosahexaenoic Acid-Like Molecules in Experimental Models of Seizures

BACKGROUND: Resistance to antiepileptic drugs and the intolerability in 20-30% of the patients raises demand for developing new drugs with improved efficacy and safety. Acceptable anticonvulsant activity, good tolerability, and inexpensiveness of docosahexaenoic acid (DHA) make it as a good candidat...

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Detalles Bibliográficos
Autores principales: Loron, Ali Gharibi, Sardari, Soroush, Narenjkar, Jamshid, Sayyah, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141252/
https://www.ncbi.nlm.nih.gov/pubmed/27592363
http://dx.doi.org/10.6091/.21.1.32