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In silico Screening and Evaluation of the Anticonvulsant Activity of Docosahexaenoic Acid-Like Molecules in Experimental Models of Seizures
BACKGROUND: Resistance to antiepileptic drugs and the intolerability in 20-30% of the patients raises demand for developing new drugs with improved efficacy and safety. Acceptable anticonvulsant activity, good tolerability, and inexpensiveness of docosahexaenoic acid (DHA) make it as a good candidat...
Autores principales: | Loron, Ali Gharibi, Sardari, Soroush, Narenjkar, Jamshid, Sayyah, Mohammad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pasteur Institute
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141252/ https://www.ncbi.nlm.nih.gov/pubmed/27592363 http://dx.doi.org/10.6091/.21.1.32 |
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