Seroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014

BACKGROUND: Retroviruses of human T-lymphotropic viruses (HTLV-1 and HTLV-2) have been demonstrated to be endemic in the north-eastern region of Iran. This study was aimed to determine the HTLV-1 and HTLV-2 prevalence among healthy individuals in Neyshabur City during 2010-2014. METHODS: A total of...

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Autores principales: Salehi, Mohammad, Mostafavi, Seyyed Khalil Shokouhi, Ghasemian, Abdolmajid, Gholami, Mahmoud, Kazemi-Vardanjani, Abdolrahim, Rahimi, Mohammad Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141255/
https://www.ncbi.nlm.nih.gov/pubmed/26899860
http://dx.doi.org/10.6091/.21.1.57
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author Salehi, Mohammad
Mostafavi, Seyyed Khalil Shokouhi
Ghasemian, Abdolmajid
Gholami, Mahmoud
Kazemi-Vardanjani, Abdolrahim
Rahimi, Mohammad Karim
author_facet Salehi, Mohammad
Mostafavi, Seyyed Khalil Shokouhi
Ghasemian, Abdolmajid
Gholami, Mahmoud
Kazemi-Vardanjani, Abdolrahim
Rahimi, Mohammad Karim
author_sort Salehi, Mohammad
collection PubMed
description BACKGROUND: Retroviruses of human T-lymphotropic viruses (HTLV-1 and HTLV-2) have been demonstrated to be endemic in the north-eastern region of Iran. This study was aimed to determine the HTLV-1 and HTLV-2 prevalence among healthy individuals in Neyshabur City during 2010-2014. METHODS: A total of 8054 blood samples were collected from healthy participants in Neyshabur, North-Eastern Iran. The blood samples were screened for the presence of specific antibodies against HTLV-1 and HTLV-2 by using ELISA according to the manufacturer’s instructions. RESULTS: The overall seropositivity rate for HTLV-1 and HTLV-2 was found to be 6.55% (528 out of 8054) among participants. CONCLUSION: Both HTLV-1 and HTLV-2 were demonstrated to be at a high rate in healthy individuals. However, a smaller number of asymptomatic carriers were found in this study, as compared to those identified in previous investigations in the city.
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spelling pubmed-51412552017-01-01 Seroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014 Salehi, Mohammad Mostafavi, Seyyed Khalil Shokouhi Ghasemian, Abdolmajid Gholami, Mahmoud Kazemi-Vardanjani, Abdolrahim Rahimi, Mohammad Karim Iran Biomed J Short Communication BACKGROUND: Retroviruses of human T-lymphotropic viruses (HTLV-1 and HTLV-2) have been demonstrated to be endemic in the north-eastern region of Iran. This study was aimed to determine the HTLV-1 and HTLV-2 prevalence among healthy individuals in Neyshabur City during 2010-2014. METHODS: A total of 8054 blood samples were collected from healthy participants in Neyshabur, North-Eastern Iran. The blood samples were screened for the presence of specific antibodies against HTLV-1 and HTLV-2 by using ELISA according to the manufacturer’s instructions. RESULTS: The overall seropositivity rate for HTLV-1 and HTLV-2 was found to be 6.55% (528 out of 8054) among participants. CONCLUSION: Both HTLV-1 and HTLV-2 were demonstrated to be at a high rate in healthy individuals. However, a smaller number of asymptomatic carriers were found in this study, as compared to those identified in previous investigations in the city. Pasteur Institute 2017-01 /pmc/articles/PMC5141255/ /pubmed/26899860 http://dx.doi.org/10.6091/.21.1.57 Text en Copyright: © Iranian Biomedical Journal http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Salehi, Mohammad
Mostafavi, Seyyed Khalil Shokouhi
Ghasemian, Abdolmajid
Gholami, Mahmoud
Kazemi-Vardanjani, Abdolrahim
Rahimi, Mohammad Karim
Seroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014
title Seroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014
title_full Seroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014
title_fullStr Seroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014
title_full_unstemmed Seroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014
title_short Seroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014
title_sort seroepidemiology of htlv-1 and htlv-2 infection in neyshabur city, north-eastern iran, during 2010-2014
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141255/
https://www.ncbi.nlm.nih.gov/pubmed/26899860
http://dx.doi.org/10.6091/.21.1.57
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