Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets

Acute myeloid leukemia (AML) is associated with poor clinical outcome and the development of more effective therapies is urgently needed. G protein-coupled receptors (GPCRs) represent attractive therapeutic targets, accounting for approximately 30% of all targets of marketed drugs. Using next-genera...

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Detalles Bibliográficos
Autores principales: Maiga, A, Lemieux, S, Pabst, C, Lavallée, V-P, Bouvier, M, Sauvageau, G, Hébert, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141352/
https://www.ncbi.nlm.nih.gov/pubmed/27258612
http://dx.doi.org/10.1038/bcj.2016.36

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