Cargando…

Context-Specific and Immune Cell-Dependent Antitumor Activities of α1-Antitrypsin

α1-antitrypsin (AAT), a circulating glycoprotein that rises during acute phase responses and healthy pregnancies, exhibits immunomodulatory properties in several T-cell-dependent immune pathologies. However, AAT does not directly interfere with T-cell responses; instead, it facilitates polarization...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guttman, Ofer, Freixo-Lima, Gabriella S., Kaner, Ziv, Lior, Yotam, Rider, Peleg, Lewis, Eli C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141363/ https://www.ncbi.nlm.nih.gov/pubmed/28003813 http://dx.doi.org/10.3389/fimmu.2016.00559

Ejemplares similares

T Helper Subsets, Peripheral Plasticity, and the Acute Phase Protein, α1-Antitrypsin
por: Baranovski, Boris M., et al.
Publicado: (2015)

S-Nitrosylation of α1-Antitrypsin Triggers Macrophages Toward Inflammatory Phenotype and Enhances Intra-Cellular Bacteria Elimination
por: Kaner, Ziv, et al.
Publicado: (2019)

Point Mutation of a Non-Elastase-Binding Site in Human α1-Antitrypsin Alters Its Anti-Inflammatory Properties
por: Lior, Yotam, et al.
Publicado: (2018)

Accelerated Wound Border Closure Using a Microemulsion Containing Non-Inhibitory Recombinant α1-Antitrypsin
por: Gimmon, Alon, et al.
Publicado: (2022)

Human α1-Antitrypsin Binds to Heat-Shock Protein gp96 and Protects from Endogenous gp96-Mediated Injury In vivo
por: Ochayon, David E., et al.
Publicado: (2013)

Chromosome instability and aneuploidy as context-dependent activators or inhibitors of antitumor immunity
por: Kuang, Xiaohong, et al.
Publicado: (2022)

Unique Versus Redundant Functions of IL-1α and IL-1β in the Tumor Microenvironment
por: Voronov, Elena, et al.
Publicado: (2013)

α(1)-Antitrypsin deficiency and chronic respiratory disorders
por: Cazzola, Mario, et al.
Publicado: (2020)

A Context-Dependent Role for αv Integrins in Regulatory T Cell Accumulation at Sites of Inflammation
por: Mair, Iris, et al.
Publicado: (2018)

Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils
por: Lee, Jungnam, et al.
Publicado: (2020)

Update on α(1)-antitrypsin deficiency
por: Ferrarotti, Ilaria, et al.
Publicado: (2018)

Fractional exhaled Nitric Oxide (FeNO) level as a predictor of COVID-19 disease severity
por: Lior, Yotam, et al.
Publicado: (2022)

Alpha-1 Antitrypsin Attenuates M1 Microglia-Mediated Neuroinflammation in Retinal Degeneration
por: Zhou, Tian, et al.
Publicado: (2018)

The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells
por: Rider, Peleg, et al.
Publicado: (2012)

Evaluation of Alpha-1 Antitrypsin Levels and SERPINA1 Gene Polymorphisms in Sickle Cell Disease
por: Carvalho, Magda Oliveira Seixas, et al.
Publicado: (2017)

Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria
por: Bai, Xiyuan, et al.
Publicado: (2019)

Alpha-1 antitrypsin limits neutrophil extracellular trap disruption of airway epithelial barrier function
por: Hudock, K. M., et al.
Publicado: (2023)

α(1)-Antitrypsin and the serpins: variation and countervariation
por: Carrell, Robin, et al.
Publicado: (1985)

Exploration of α1-Antitrypsin Treatment Protocol for Islet Transplantation: Dosing Plan and Route of Administration
por: Baranovski, Boris M., et al.
Publicado: (2016)

The Antitumor Activity of Combinations of Cytotoxic Chemotherapy and Immune Checkpoint Inhibitors Is Model-Dependent
por: Grasselly, Chloé, et al.
Publicado: (2018)

T-Cell-Specific Loss of the PI-3-Kinase p110α Catalytic Subunit Results in Enhanced Cytokine Production and Antitumor Response
por: Aragoneses-Fenoll, Laura, et al.
Publicado: (2018)

Sense and Immunity: Context-Dependent Neuro-Immune Interplay
por: Foster, Simmie L., et al.
Publicado: (2017)

Imbalance of NET and Alpha-1-Antitrypsin in Tuberculosis Patients Is Related With Hyper Inflammation and Severe Lung Tissue Damage
por: de Melo, Mayla Gabryele Miranda, et al.
Publicado: (2019)

Concentration-dependent effects of native and polymerised α1-antitrypsin on primary human monocytes, in vitro
por: Aldonyte, Ruta, et al.
Publicado: (2004)

Appropriateness of Newborn Screening for α1-Antitrypsin Deficiency
por: Teckman, Jeffrey, et al.
Publicado: (2014)

Ruptured Gastric Aneurysm in α-1 Antitrypsin Deficiency
por: Jaruvongvanich, Veeravich, et al.
Publicado: (2016)

Molecular Mechanism of Z α1-Antitrypsin Deficiency
por: Huang, Xin, et al.
Publicado: (2016)

IS THERE A ROLE FOR α1-ANTITRYPSIN IN COVID-19?
por: Gurbel, Paul A., et al.
Publicado: (2021)

A specific proteinase 3 activity footprint in α(1)-antitrypsin deficiency
por: Newby, Paul R., et al.
Publicado: (2019)

IL-31 induces antitumor immunity in breast carcinoma
por: Kan, Tal, et al.
Publicado: (2020)

Context Is Key: Delineating the Unique Functions of IFNα and IFNβ in Disease
por: Fox, Lindsey E., et al.
Publicado: (2020)

Temporal force governs the microbial assembly associated with Ulva fasciata (Chlorophyta) from an integrated multi-trophic aquaculture system
por: Nguyen, Dzung, et al.
Publicado: (2023)

Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors
por: Siebers, Kathrin, et al.
Publicado: (2018)

Secretion of functional α1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy
por: Ke, Haiping, et al.
Publicado: (2022)

Ranitidine Inhibition of Breast Tumor Growth Is B Cell Dependent and Associated With an Enhanced Antitumor Antibody Response
por: Rogers, Dakota, et al.
Publicado: (2018)

Neurofibromin 1 Impairs Natural Killer T-Cell-Dependent Antitumor Immunity against a T-Cell Lymphoma
por: Liu, Jianyun, et al.
Publicado: (2018)

Prevalence of α-1-Antitrypsin Gene Mutations in Saudi Arabia
por: Aljarallah, Badr, et al.
Publicado: (2011)

Stem cell-based therapy for α(1)-antitrypsin deficiency
por: Rashid, S Tamir, et al.
Publicado: (2012)

Deficiency of α-1-antitrypsin influences systemic iron homeostasis
por: Ghio, Andrew J, et al.
Publicado: (2013)

Flecainide and elevated liver enzymes in α1-antitrypsin deficiency
por: Jenkins, David J.A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_hbb7u5r4o4ah2n6mldllotn5oe