Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes

Netrins, a family of laminin-related molecules, have been proposed to act as guidance cues either during nervous system development or the establishment of the vascular system. This was clearly demonstrated for netrin-1 via its interaction with the receptors DCC and UNC5s. However, mainly based on s...

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Detalles Bibliográficos
Autores principales: Reuten, Raphael, Patel, Trushar R., McDougall, Matthew, Rama, Nicolas, Nikodemus, Denise, Gibert, Benjamin, Delcros, Jean-Guy, Prein, Carina, Meier, Markus, Metzger, Stéphanie, Zhou, Zhigang, Kaltenberg, Jennifer, McKee, Karen K., Bald, Tobias, Tüting, Thomas, Zigrino, Paola, Djonov, Valentin, Bloch, Wilhelm, Clausen-Schaumann, Hauke, Poschl, Ernst, Yurchenco, Peter D., Ehrbar, Martin, Mehlen, Patrick, Stetefeld, Jörg, Koch, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141367/
https://www.ncbi.nlm.nih.gov/pubmed/27901020
http://dx.doi.org/10.1038/ncomms13515

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