Cargando…
Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding
Small heat shock proteins (sHsp) constitute an evolutionary conserved yet diverse family of chaperones acting as first line of defence against proteotoxic stress. sHsps coaggregate with misfolded proteins but the molecular basis and functional implications of these interactions, as well as potential...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141385/ https://www.ncbi.nlm.nih.gov/pubmed/27901028 http://dx.doi.org/10.1038/ncomms13673 |