Cargando…

The secretome of periodontal ligament stem cells from MS patients protects against EAE

Manipulation of stem cells or stem cells-derived secretome has emerged as a novel alternative therapeutic option for multiple sclerosis (MS). Here we show that human periodontal ligament stem cells (hPDLSCs)-derived conditioned medium (hPDLSCs-CM) and purified exosomes/microvesicles (hPDLSCs-EMVs) o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rajan, Thangavelu Soundara, Giacoppo, Sabrina, Diomede, Francesca, Ballerini, Patrizia, Paolantonio, Michele, Marchisio, Marco, Piattelli, Adriano, Bramanti, Placido, Mazzon, Emanuela, Trubiani, Oriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141419/ https://www.ncbi.nlm.nih.gov/pubmed/27924938 http://dx.doi.org/10.1038/srep38743

Ejemplares similares

Human periodontal ligament stem cells secretome from multiple sclerosis patients suppresses NALP3 inflammasome activation in experimental autoimmune encephalomyelitis
por: Soundara Rajan, Thangavelu, et al.
Publicado: (2017)

Anti-inflammatory effects of hypoxia-preconditioned human periodontal ligament cell secretome in an experimental model of multiple sclerosis: a key role of IL-37
por: Giacoppo, Sabrina, et al.
Publicado: (2017)

Alternative source of stem cells derived from human periodontal ligament: a new treatment for experimental autoimmune encephalomyelitis
por: Trubiani, Oriana, et al.
Publicado: (2016)

Stemness Characteristics of Periodontal Ligament Stem Cells from Donors and Multiple Sclerosis Patients: A Comparative Study
por: Diomede, Francesca, et al.
Publicado: (2017)

Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells: Role of epigenetic modifications to the inflammation
por: Diomede, Francesca, et al.
Publicado: (2017)

Conditioned medium from human gingival mesenchymal stem cells protects motor-neuron-like NSC-34 cells against scratch-injury-induced cell death
por: Rajan, Thangavelu Soundara, et al.
Publicado: (2017)

Physiological Expression of Ion Channel Receptors in Human Periodontal Ligament Stem Cells
por: Chiricosta, Luigi, et al.
Publicado: (2019)

Human Periodontal Ligament Stem Cells Response to Titanium Implant Surface: Extracellular Matrix Deposition
por: Marconi, Guya Diletta, et al.
Publicado: (2021)

Oral Bone Tissue Regeneration: Mesenchymal Stem Cells, Secretome, and Biomaterials
por: Gugliandolo, Agnese, et al.
Publicado: (2021)

Correction: Marconi et al. Human Periodontal Ligament Stem Cells Response to Titanium Implant Surface: Extracellular Matrix Deposition. Biology 2021, 10, 931
por: Marconi, Guya Diletta, et al.
Publicado: (2023)

Stemness Maintenance Properties in Human Oral Stem Cells after Long-Term Passage
por: Diomede, Francesca, et al.
Publicado: (2017)

Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview
por: Libro, Rosaliana, et al.
Publicado: (2016)

Cannabidiol Modulates the Immunophenotype and Inhibits the Activation of the Inflammasome in Human Gingival Mesenchymal Stem Cells
por: Libro, Rosaliana, et al.
Publicado: (2016)

A novel role in skeletal segment regeneration of extracellular vesicles released from periodontal-ligament stem cells
por: Diomede, Francesca, et al.
Publicado: (2018)

Moringin Pretreatment Inhibits the Expression of Genes Involved in Mitophagy in the Stem Cell of the Human Periodontal Ligament
por: Chiricosta, Luigi, et al.
Publicado: (2019)

Moringin Induces Neural Differentiation in the Stem Cell of the Human Periodontal Ligament
por: Romeo, Letizia, et al.
Publicado: (2018)

Engineered Extracellular Vesicles From Human Periodontal-Ligament Stem Cells Increase VEGF/VEGFR2 Expression During Bone Regeneration
por: Pizzicannella, Jacopo, et al.
Publicado: (2019)

Addendum: Engineered extracellular vesicles from human periodontal-ligament stem cells increase VEGF/VEGFR2 expression during bone regeneration
por: Pizzicannella, Jacopo, et al.
Publicado: (2023)

Moringin activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis
por: Giacoppo, Sabrina, et al.
Publicado: (2016)

Cannabidiol Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells
por: Libro, Rosaliana, et al.
Publicado: (2016)

Treatment of Periodontal Ligament Stem Cells with MOR and CBD Promotes Cell Survival and Neuronal Differentiation via the PI3K/Akt/mTOR Pathway
por: Lanza Cariccio, Veronica, et al.
Publicado: (2018)

Enhanced VEGF/VEGF-R and RUNX2 Expression in Human Periodontal Ligament Stem Cells Cultured on Sandblasted/Etched Titanium Disk
por: Marconi, Guya Diletta, et al.
Publicado: (2020)

In Vitro-Transcribed mRNA Chimeric Antigen Receptor T Cell (IVT mRNA CAR T) Therapy in Hematologic and Solid Tumor Management: A Preclinical Update
por: Soundara Rajan, Thangavelu, et al.
Publicado: (2020)

Tunneling Nanotubes-Mediated Protection of Mesenchymal Stem Cells: An Update from Preclinical Studies
por: Soundara Rajan, Thangavelu, et al.
Publicado: (2020)

The Role of Hypoxia on the Neuronal Differentiation of Gingival Mesenchymal Stem Cells: A Transcriptional Study
por: Gugliandolo, Agnese, et al.
Publicado: (2019)

Cannabinoid CB2 Receptors are Involved in the Protection of RAW264.7 Macrophages Against the Oxidative Stress: An in Vitro Study
por: Giacoppo, Sabrina, et al.
Publicado: (2017)

Potential Anti-Inflammatory Effects of a New Lyophilized Formulation of the Conditioned Medium Derived from Periodontal Ligament Stem Cells
por: Gugliandolo, Agnese, et al.
Publicado: (2022)

Extracellular Vesicles of Human Periodontal Ligament Stem Cells Contain MicroRNAs Associated to Proto-Oncogenes: Implications in Cytokinesis
por: Chiricosta, Luigi, et al.
Publicado: (2020)

Role of Cortico-Cancellous Heterologous Bone in Human Periodontal Ligament Stem Cell Xeno-Free Culture Studied by Synchrotron Radiation Phase-Contrast Microtomography
por: Mazzoni, Serena, et al.
Publicado: (2017)

Transcriptomic Analysis of Stem Cells Treated with Moringin or Cannabidiol: Analogies and Differences in Inflammation Pathways
por: Chiricosta, Luigi, et al.
Publicado: (2019)

Stem Cells Therapy for Spinal Cord Injury: An Overview of Clinical Trials
por: Silvestro, Serena, et al.
Publicado: (2020)

Extracellular Vesicles Derived from Human Gingival Mesenchymal Stem Cells: A Transcriptomic Analysis
por: Silvestro, Serena, et al.
Publicado: (2020)

MicroRNA Profiling of HL-1 Cardiac Cells-Derived Extracellular Vesicles
por: Silvestro, Serena, et al.
Publicado: (2021)

Functional Relationship between Osteogenesis and Angiogenesis in Tissue Regeneration
por: Diomede, Francesca, et al.
Publicado: (2020)

Salivary Biomarkers: Future Approaches for Early Diagnosis of Neurodegenerative Diseases
por: Schepici, Giovanni, et al.
Publicado: (2020)

3D Printing PLA/Gingival Stem Cells/ EVs Upregulate miR-2861 and -210 during Osteoangiogenesis Commitment
por: Pizzicannella, Jacopo, et al.
Publicado: (2019)

Triggering of inflammasome by impaired autophagy in response to acute experimental Parkinson’s disease: involvement of the PI3K/Akt/mTOR pathway
por: Giacoppo, Sabrina, et al.
Publicado: (2017)

Antioxidant Ascorbic Acid Modulates NLRP3 Inflammasome in LPS-G Treated Oral Stem Cells through NFκB/Caspase-1/IL-1β Pathway
por: Pizzicannella, Jacopo, et al.
Publicado: (2021)

Inhibition of LPS-Induced Inflammatory Response of Oral Mesenchymal Stem Cells in the Presence of Galectin-3
por: Paganelli, Alessia, et al.
Publicado: (2023)

VEGF/VEGF-R/RUNX2 Upregulation in Human Periodontal Ligament Stem Cells Seeded on Dual Acid Etched Titanium Disk
por: Diomede, Francesca, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7rvncdr56sg5dkh42pqqbsb4oa