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Mesenchymal stem cell transplantation can restore lupus disease-associated miRNA expression and Th1/Th2 ratios in a murine model of SLE

C3.MRL-Fas(lpr)/J mice spontaneously develop high titers of anti-dsDNA, mild glomerular nephritis, and severe lymphoproliferation symptoms. This study aimed to compare the effects of long-term serial administration of human adipose tissue-derived mesenchymal stem cells (ASCs), and cyclophosphamide t...

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Detalles Bibliográficos
Autores principales: Choi, Eun Wha, Lee, MinJae, Song, Ji Woo, Shin, Il Seob, Kim, Sung Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141468/
https://www.ncbi.nlm.nih.gov/pubmed/27924862
http://dx.doi.org/10.1038/srep38237