Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome

The homeodomain transcription factor distal-less homeobox 3 gene (DLX3) is required for hair, tooth and skeletal development. DLX3 mutations have been found to be responsible for Tricho-Dento-Osseous (TDO) syndrome, characterized by kinky hair, thin-pitted enamel and increased bone density. Here we...

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Detalles Bibliográficos
Autores principales: Zhao, Na, Han, Dong, Liu, Haochen, Li, Yue, Wong, Sing-Wai, Cao, Zhengyi, Xu, Jian, Zhang, Xiaowei, Cai, Tao, Wang, Yixiang, Feng, Hailan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141470/
https://www.ncbi.nlm.nih.gov/pubmed/27924851
http://dx.doi.org/10.1038/srep38680

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