rpL3 promotes the apoptosis of p53 mutated lung cancer cells by down-regulating CBS and NFκB upon 5-FU treatment

5-FU is a chemotherapy drug commonly used for the treatment of human cancers; however drug resistance represents a major challenge for its clinical application. In the present study, we reporte that rpL3 induced by 5-FU treatment in Calu-6 cells represses CBS transcription and reduces CBS protein st...

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Detalles Bibliográficos
Autores principales: Russo, Annapina, Saide, Assunta, Cagliani, Roberta, Cantile, Monica, Botti, Gerardo, Russo, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141482/
https://www.ncbi.nlm.nih.gov/pubmed/27924828
http://dx.doi.org/10.1038/srep38369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141482/
https://www.ncbi.nlm.nih.gov/pubmed/27924828
http://dx.doi.org/10.1038/srep38369

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