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NADPH oxidase 4 deficiency increases tubular cell death during acute ischemic reperfusion injury

NADPH oxidase 4 (NOX4) is highly expressed in kidney proximal tubular cells. NOX4 constitutively produces hydrogen peroxide, which may regulate important pro-survival pathways. Renal ischemia reperfusion injury (IRI) is a classical model mimicking human ischemic acute tubular necrosis. We hypothesiz...

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Detalles Bibliográficos
Autores principales:	Nlandu-Khodo, Stellor, Dissard, Romain, Hasler, Udo, Schäfer, Matthias, Pircher, Haymo, Jansen-Durr, Pidder, Krause, Karl Heinz, Martin, Pierre-Yves, de Seigneux, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141508/ https://www.ncbi.nlm.nih.gov/pubmed/27924932 http://dx.doi.org/10.1038/srep38598

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