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Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells
To fulfil the bioenergetic requirements for increased cell size and clonal expansion, activated T cells reprogramme their metabolic signatures from energetically quiescent to activated. However, the molecular mechanisms and essential components controlling metabolic reprogramming in T cells are not...
Autores principales: | Angela, Mulki, Endo, Yusuke, Asou, Hikari K., Yamamoto, Takeshi, Tumes, Damon J., Tokuyama, Hirotake, Yokote, Koutaro, Nakayama, Toshinori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141517/ https://www.ncbi.nlm.nih.gov/pubmed/27901044 http://dx.doi.org/10.1038/ncomms13683 |
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