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A Fluorescence Polarization Biophysical Assay for the Naegleria DNA Hydroxylase Tet1
[Image: see text] The discovery of the 5-methylcytosine (5mC) oxidation by the ten–eleven translocation (Tet) protein family was an important advancement in our understanding of DNA-modified epigenetics. Potent inhibitors of these proteins are greatly desired for both the understanding of the functi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141568/ https://www.ncbi.nlm.nih.gov/pubmed/27980707 http://dx.doi.org/10.1021/acsmedchemlett.5b00366 |