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A Fluorescence Polarization Biophysical Assay for the Naegleria DNA Hydroxylase Tet1

[Image: see text] The discovery of the 5-methylcytosine (5mC) oxidation by the ten–eleven translocation (Tet) protein family was an important advancement in our understanding of DNA-modified epigenetics. Potent inhibitors of these proteins are greatly desired for both the understanding of the functi...

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Detalles Bibliográficos
Autores principales: Marholz, Laura J., Wang, Wei, Zheng, Yu, Wang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141568/
https://www.ncbi.nlm.nih.gov/pubmed/27980707
http://dx.doi.org/10.1021/acsmedchemlett.5b00366