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Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia
BACKGROUND: Intracellular signaling through cyclic nucleotides, both cyclic AMP and cyclic GMP, is altered in colorectal cancer. Accordingly, it is hypothesized that an underlying mechanism for colorectal neoplasia involves altered function of phosphodiesterases (PDEs), which affects cyclic nucleoti...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141637/ https://www.ncbi.nlm.nih.gov/pubmed/27927168 http://dx.doi.org/10.1186/s12885-016-2980-z |