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Antibodies Against the Current Influenza A(H1N1) Vaccine Strain Do Not Protect Some Individuals From Infection With Contemporary Circulating Influenza A(H1N1) Virus Strains

During the 2013–2014 influenza season, nearly all circulating 2009 pandemic influenza A(H1N1) virus (A[H1N1]pdm09) strains possessed an antigenically important mutation in hemagglutinin (K166Q). Here, we performed hemagglutination-inhibition (HAI) assays, using sera collected from 382 individuals pr...

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Detalles Bibliográficos
Autores principales: Petrie, Joshua G., Parkhouse, Kaela, Ohmit, Suzanne E., Malosh, Ryan E., Monto, Arnold S., Hensley, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142093/
https://www.ncbi.nlm.nih.gov/pubmed/27923954
http://dx.doi.org/10.1093/infdis/jiw479