Cargando…

srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer

BACKGROUND: The neuronal guidance molecule Slit2 plays suppressive role in tumorigenesis and progression. We previously showed that Slit2-Robo1 inhibit cell migration in colorectal cancer (CRC). However, little is known about its downstream effectors in CRC. This study tries to identify whether the...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Yuyang, Feng, Lei, Yu, Di, Zou, Jian, Huang, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142155/
https://www.ncbi.nlm.nih.gov/pubmed/27923383
http://dx.doi.org/10.1186/s13046-016-0469-x