Sudden death due to paralysis and synaptic and behavioral deficits when Hip14/Zdhhc17 is deleted in adult mice

BACKGROUND: Palmitoylation, the addition of palmitate to proteins by palmitoyl acyltransferases (PATs), is an important regulator of synaptic protein localization and function. Many palmitoylated proteins and PATs have been implicated in neuropsychiatric diseases, including Huntington disease, schiz...

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Detalles Bibliográficos
Autores principales: Sanders, Shaun S., Parsons, Matthew P., Mui, Katherine K. N., Southwell, Amber L., Franciosi, Sonia, Cheung, Daphne, Waltl, Sabine, Raymond, Lynn A., Hayden, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142322/
https://www.ncbi.nlm.nih.gov/pubmed/27927242
http://dx.doi.org/10.1186/s12915-016-0333-7

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