Genetic variations of aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B are associated with the etiology of atrial fibrillation in Japanese

BACKGROUND: Alcohol consumption and oxidative stress are well-known risk factors for developing atrial fibrillation (AF). Single nucleotide polymorphisms (SNPs) of alcohol dehydrogenase (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) genes encoding enzymes of alcohol and reactive aldehyde metabolism, r...

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Detalles Bibliográficos
Autores principales: Nakano, Yukiko, Ochi, Hidenori, Onohara, Yuko, Sairaku, Akinori, Tokuyama, Takehito, Matsumura, Hiroya, Tomomori, Shunsuke, Amioka, Michitaka, Hironomobe, Naoya, Motoda, Chikaaki, Oda, Nozomu, Chayama, Kazuaki, Chen, Che-Hong, Gross, Eric R., Mochly-Rosen, Daria, Kihara, Yasuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142328/
https://www.ncbi.nlm.nih.gov/pubmed/27927211
http://dx.doi.org/10.1186/s12929-016-0304-x

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