Cargando…
Molecular control of nitric oxide synthesis through eNOS and caveolin-1 interaction regulates osteogenic differentiation of adipose-derived stem cells by modulation of Wnt/β-catenin signaling
BACKGROUND: Nitric oxide (NO) plays a role in a number of physiological processes including stem cell differentiation and osteogenesis. Endothelial nitric oxide synthase (eNOS), one of three NO-producing enzymes, is located in a close conformation with the caveolin-1 (CAV-1(WT)) membrane protein whi...
Autores principales: | Bandara, Nadeeka, Gurusinghe, Saliya, Lim, Shiang Yong, Chen, Haying, Chen, Shuangfeng, Wang, Dawei, Hilbert, Bryan, Wang, Le-Xin, Strappe, Padraig |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142348/ https://www.ncbi.nlm.nih.gov/pubmed/27927230 http://dx.doi.org/10.1186/s13287-016-0442-9 |
Ejemplares similares
-
Minicircle DNA-mediated endothelial nitric oxide synthase gene transfer enhances angiogenic responses of bone marrow-derived mesenchymal stem cells
por: Bandara, Nadeeka, et al.
Publicado: (2016) -
Gene Modification of Mesenchymal Stem Cells and Articular Chondrocytes to Enhance Chondrogenesis
por: Gurusinghe, Saliya, et al.
Publicado: (2014) -
Nitric oxide–dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition
por: Chen, Zhenlong, et al.
Publicado: (2012) -
Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells
por: Chen, Zhenlong, et al.
Publicado: (2018) -
Induction of caveolin-3/eNOS complex by nitroxyl (HNO) ameliorates diabetic cardiomyopathy
por: Sun, Hai-Jian, et al.
Publicado: (2020)