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LRRK2 at the interface of autophagosomes, endosomes and lysosomes

Over the past 20 years, substantial progress has been made in identifying the underlying genetics of Parkinson’s disease (PD). Of the known genes, LRRK2 is a major genetic contributor to PD. However, the exact function of LRRK2 remains to be elucidated. In this review, we discuss how familial forms...

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Detalles Bibliográficos
Autores principales: Roosen, Dorien A., Cookson, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142374/
https://www.ncbi.nlm.nih.gov/pubmed/27927216
http://dx.doi.org/10.1186/s13024-016-0140-1