Detection of Theileria parva in tissues of cattle undergoing severe East Coast fever disease show significant parasite DNA accumulation in the spleen

Infiltration and proliferation of Theileria parva infected lymphocytes in bovine host lymphoid organs is one of the hallmarks of T. parva infection. The relative abundance of parasites within infected host tissues, both lymphoid and non-lymphoid is however unknown. Using quantitative PCR, we have sh...

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Autores principales: Olds, Cassandra L., Paul, Tasha, Scoles, Glen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142468/
https://www.ncbi.nlm.nih.gov/pubmed/27890079
http://dx.doi.org/10.1016/j.vetpar.2016.11.012
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author Olds, Cassandra L.
Paul, Tasha
Scoles, Glen A.
author_facet Olds, Cassandra L.
Paul, Tasha
Scoles, Glen A.
author_sort Olds, Cassandra L.
collection PubMed
description Infiltration and proliferation of Theileria parva infected lymphocytes in bovine host lymphoid organs is one of the hallmarks of T. parva infection. The relative abundance of parasites within infected host tissues, both lymphoid and non-lymphoid is however unknown. Using quantitative PCR, we have shown that significantly higher concentrations of T. parva DNA are detected in the spleens of cattle undergoing severe disease compared to other organs.
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spelling pubmed-51424682016-12-15 Detection of Theileria parva in tissues of cattle undergoing severe East Coast fever disease show significant parasite DNA accumulation in the spleen Olds, Cassandra L. Paul, Tasha Scoles, Glen A. Vet Parasitol Short Communication Infiltration and proliferation of Theileria parva infected lymphocytes in bovine host lymphoid organs is one of the hallmarks of T. parva infection. The relative abundance of parasites within infected host tissues, both lymphoid and non-lymphoid is however unknown. Using quantitative PCR, we have shown that significantly higher concentrations of T. parva DNA are detected in the spleens of cattle undergoing severe disease compared to other organs. Elsevier 2016-12-15 /pmc/articles/PMC5142468/ /pubmed/27890079 http://dx.doi.org/10.1016/j.vetpar.2016.11.012 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Short Communication
Olds, Cassandra L.
Paul, Tasha
Scoles, Glen A.
Detection of Theileria parva in tissues of cattle undergoing severe East Coast fever disease show significant parasite DNA accumulation in the spleen
title Detection of Theileria parva in tissues of cattle undergoing severe East Coast fever disease show significant parasite DNA accumulation in the spleen
title_full Detection of Theileria parva in tissues of cattle undergoing severe East Coast fever disease show significant parasite DNA accumulation in the spleen
title_fullStr Detection of Theileria parva in tissues of cattle undergoing severe East Coast fever disease show significant parasite DNA accumulation in the spleen
title_full_unstemmed Detection of Theileria parva in tissues of cattle undergoing severe East Coast fever disease show significant parasite DNA accumulation in the spleen
title_short Detection of Theileria parva in tissues of cattle undergoing severe East Coast fever disease show significant parasite DNA accumulation in the spleen
title_sort detection of theileria parva in tissues of cattle undergoing severe east coast fever disease show significant parasite dna accumulation in the spleen
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142468/
https://www.ncbi.nlm.nih.gov/pubmed/27890079
http://dx.doi.org/10.1016/j.vetpar.2016.11.012
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AT scolesglena detectionoftheileriaparvaintissuesofcattleundergoingsevereeastcoastfeverdiseaseshowsignificantparasitednaaccumulationinthespleen

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