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Lysine-Specific Demethylase 1 (LSD1) Inhibitor S2101 Induces Autophagy via the AKT/mTOR Pathway in SKOV3 Ovarian Cancer Cells

BACKGROUND: S2101 is one of the most potent LSD1 inhibitors, which can inhibit ovarian cancer cells viability. This study aimed to detect the mechanism behind the anticancer properties of S2101 in SKOV3 ovarian cells. MATERIAL/METHODS: Cell viability was tested by Cell Counting Kit-8 (CCK-8) assay....

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Detalles Bibliográficos
Autores principales:	Feng, Shujun, Jin, Ye, Cui, Mengjiao, Zheng, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2016
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142589/ https://www.ncbi.nlm.nih.gov/pubmed/27914215 http://dx.doi.org/10.12659/MSM.898825

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