AB300. SPR-27 Sonic hedgehog promotes sprouting of neurons in the pelvic ganglia and cavernous nerve during regeneration

OBJECTIVE: We’ve shown in previous studies that sonic hedgehog (SHH) protein delivered by nanoparticle based peptide amphiphile (PA) hydrogels to the cavernous nerve (CN) at the time of crush injury (mimicking prostatectomy), are neuroprotective and promote CN regeneration in a rat model. The mechan...

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Detalles Bibliográficos
Autores principales: Dobbs, Ryan, Choe, Shawn, Harrington, Daniel A., Stupp, Samuel I., McVary, Kevin T., Podlasek, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143243/
http://dx.doi.org/10.21037/tau.2016.s300

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