AB302. SPR-29 Sphingosine-1-phosphate in vitro and in vivo modulates corpus cavernosum smooth muscle tone

OBJECTIVE: The bioactive lipid sphingosine-1-phosphate (S1P) regulates smooth muscle (SM) contractility predominantly via three G protein-coupled receptors. The S1P1 receptor is associated with nitric oxide-mediated SM relaxation while S1P2 & S1P3 receptors are linked to SM contraction via activ...

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Detalles Bibliográficos
Autores principales: Zhang, Xinhua, Yin, Jing, Kanika, Nirmala D., Tong, Yuehong, Villegas, Guillermo, Melman, Arnold, DiSanto, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143250/
http://dx.doi.org/10.21037/tau.2016.s302

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