AB315. SPR-42 Cyclophosphamide-induced overactive bladder via downregulation of relaxation factors in detrusor PDGFRα(+) cells

OBJECTIVE: Morphology and functional role of PDGFRα(+) cells have been recently characterized in the detrusor muscle layer. Detrusor relaxation is caused by activation of small conductance Ca(2+) activated-K(+) (SK) channels and purinergic inhibitory responses in detrusor PDGFRα(+) cells. Loss of PD...

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Detalles Bibliográficos
Autores principales: Lee, Haeyeong, Koh, Byoung H., Corrigan, Robert D., Peri, Lauren E., Sanders, Kenton M., Chai, Toby C., Koh, Sang Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143253/
http://dx.doi.org/10.21037/tau.2016.s315

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