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Erianin induces G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells in vitro and in vivo

Erianin, a natural product derived from Dendrobium chrysotoxum, has exhibited potential antitumor activity in various malignancies, including hepatocarcinoma, melanoma, and promyelocytic leukemia. Here we explored the effects of erianin on osteosarcoma (OS) in vitro and in vivo and further elucidate...

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Detalles Bibliográficos
Autores principales: Wang, H, Zhang, T, Sun, W, Wang, Z, Zuo, D, Zhou, Z, Li, S, Xu, J, Yin, F, Hua, Y, Cai, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143374/
https://www.ncbi.nlm.nih.gov/pubmed/27253411
http://dx.doi.org/10.1038/cddis.2016.138