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A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment

We have used polysome profiling coupled to microarray analysis to examine the translatome of a panel of peripheral blood (PB) B cells isolated from 34 chronic lymphocytic leukaemia (CLL) patients. We have identified a ‘ribosome-related' signature in CLL patients with mRNAs encoding for ribosoma...

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Detalles Bibliográficos
Autores principales:	Sbarrato, T, Horvilleur, E, Pöyry, T, Hill, K, Chaplin, L C, Spriggs, R V, Stoneley, M, Wilson, L, Jayne, S, Vulliamy, T, Beck, D, Dokal, I, Dyer, M J S, Yeomans, A M, Packham, G, Bushell, M, Wagner, S D, Willis, A E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143378/ https://www.ncbi.nlm.nih.gov/pubmed/27253413 http://dx.doi.org/10.1038/cddis.2016.148

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