Expression of μ-protocadherin is negatively regulated by the activation of the β-catenin signaling pathway in normal and cancer colorectal enterocytes

Mu-protocadherin (MUCDHL) is an adhesion molecule predominantly expressed by colorectal epithelial cells which is markedly downregulated upon malignant transformation. Notably, treatment of colorectal cancer (CRC) cells with mesalazine lead to increased expression of MUCDHL, and is associated with s...

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Detalles Bibliográficos
Autores principales: Montorsi, L, Parenti, S, Losi, L, Ferrarini, F, Gemelli, C, Rossi, A, Manco, G, Ferrari, S, Calabretta, B, Tagliafico, E, Zanocco-Marani, T, Grande, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143391/
https://www.ncbi.nlm.nih.gov/pubmed/27310872
http://dx.doi.org/10.1038/cddis.2016.163

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