Endoplasmic reticulum stress eIF2α–ATF4 pathway-mediated cyclooxygenase-2 induction regulates cadmium-induced autophagy in kidney

The heavy metal cadmium (Cd) is nephrotoxic. Recent studies show that autophagy plays an essential role in Cd-induced kidney injury. However, the mechanisms of Cd-induced kidney injury accompanied by autophagy are still obscure. In the present study, we first confirmed that Cd induced kidney damage...

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Detalles Bibliográficos
Autores principales: Luo, B, Lin, Y, Jiang, S, Huang, L, Yao, H, Zhuang, Q, Zhao, R, Liu, H, He, C, Lin, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143407/
https://www.ncbi.nlm.nih.gov/pubmed/27253415
http://dx.doi.org/10.1038/cddis.2016.78

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