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Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis

Fatty acid biosynthesis (FAS) is a vital process in cells. Fatty acids are essential for cell assembly and cellular metabolism. Abnormal FAS directly correlates with cell growth delay and human diseases, such as metabolic syndromes and various cancers. The FAS system utilizes an acyl carrier protein...

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Detalles Bibliográficos
Autores principales:	Zhang, Lin, Xiao, Jianfeng, Xu, Jianrong, Fu, Tianran, Cao, Zhiwei, Zhu, Liang, Chen, Hong-Zhuan, Shen, Xu, Jiang, Hualiang, Zhang, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143422/ https://www.ncbi.nlm.nih.gov/pubmed/27874013 http://dx.doi.org/10.1038/cr.2016.136

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