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Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway
BACKGROUND: Many pathogens secrete toxins that target key host processes resulting in the activation of immune pathways. The secreted Pseudomonas aeruginosa toxin Exotoxin A (ToxA) disrupts intestinal protein synthesis, which triggers the induction of a subset of P. aeruginosa-response genes in the...
Autores principales: | McEwan, Deborah L., Feinbaum, Rhonda L., Stroustrup, Nicholas, Haas, Wilhelm, Conery, Annie L., Anselmo, Anthony, Sadreyev, Ruslan, Ausubel, Frederick M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143455/ https://www.ncbi.nlm.nih.gov/pubmed/27927200 http://dx.doi.org/10.1186/s12915-016-0334-6 |
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