The Protective Role of microRNA-200c in Alzheimer's Disease Pathologies Is Induced by Beta Amyloid-Triggered Endoplasmic Reticulum Stress

MicroRNAs are small non-coding RNAs that repress the expression of their target proteins. The roles of microRNAs in the development of Alzheimer's disease (AD) are not clear. In this study we show that miR-200c represses the expression of PTEN protein. PTEN downregulation by miR-200c supports t...

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Detalles Bibliográficos
Autores principales: Wu, Qi, Ye, Xiaoyang, Xiong, Yi, Zhu, Haili, Miao, Jianting, Zhang, Wei, Wan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143617/
https://www.ncbi.nlm.nih.gov/pubmed/28008308
http://dx.doi.org/10.3389/fnmol.2016.00140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143617/
https://www.ncbi.nlm.nih.gov/pubmed/28008308
http://dx.doi.org/10.3389/fnmol.2016.00140

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