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Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal

Background. Superficial mycosis is a common fungal infection worldwide, mainly caused by dermatophytes. However, the prevalence of species varies geographically. In addition, fungal treatment is best guided according to species isolated. This study was carried out to determine the clinical as well a...

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Autores principales: Khadka, Sundar, Sherchand, Jeevan Bahadur, Pokharel, Dinesh Binod, Pokhrel, Bharat Mani, Mishra, Shyam Kumar, Dhital, Subhash, Rijal, Basista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143727/
https://www.ncbi.nlm.nih.gov/pubmed/28003819
http://dx.doi.org/10.1155/2016/9509705
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author Khadka, Sundar
Sherchand, Jeevan Bahadur
Pokharel, Dinesh Binod
Pokhrel, Bharat Mani
Mishra, Shyam Kumar
Dhital, Subhash
Rijal, Basista
author_facet Khadka, Sundar
Sherchand, Jeevan Bahadur
Pokharel, Dinesh Binod
Pokhrel, Bharat Mani
Mishra, Shyam Kumar
Dhital, Subhash
Rijal, Basista
author_sort Khadka, Sundar
collection PubMed
description Background. Superficial mycosis is a common fungal infection worldwide, mainly caused by dermatophytes. However, the prevalence of species varies geographically. In addition, fungal treatment is best guided according to species isolated. This study was carried out to determine the clinical as well as mycological profile of superficial mycoses in a tertiary care hospital, Nepal. Methods. This was a prospective case-control laboratory based study conducted over a period of six months from January to June 2014 at Tribhuvan University Teaching Hospital, Nepal. A total of 200 specimens were collected from the patients suspected of superficial mycoses. The specimens were macroscopically as well as microscopically examined. The growth was observed up to 4 weeks. Results. Out of total 200 specimens from the patients suspected of superficial mycoses, tinea corporis 50 (25%) was most common clinical types. KOH mount was positive in 89 (44.5%) and culture was positive in 111 (55.5%). Trichophyton mentagrophytes 44 (39.6%) was the most common isolate. Conclusions. The diagnostic yields of KOH mount and culture were found to be complementary to each other. Thus both the methods added with clinical findings are equally important to establish superficial mycosis.
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spelling pubmed-51437272016-12-21 Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal Khadka, Sundar Sherchand, Jeevan Bahadur Pokharel, Dinesh Binod Pokhrel, Bharat Mani Mishra, Shyam Kumar Dhital, Subhash Rijal, Basista Dermatol Res Pract Research Article Background. Superficial mycosis is a common fungal infection worldwide, mainly caused by dermatophytes. However, the prevalence of species varies geographically. In addition, fungal treatment is best guided according to species isolated. This study was carried out to determine the clinical as well as mycological profile of superficial mycoses in a tertiary care hospital, Nepal. Methods. This was a prospective case-control laboratory based study conducted over a period of six months from January to June 2014 at Tribhuvan University Teaching Hospital, Nepal. A total of 200 specimens were collected from the patients suspected of superficial mycoses. The specimens were macroscopically as well as microscopically examined. The growth was observed up to 4 weeks. Results. Out of total 200 specimens from the patients suspected of superficial mycoses, tinea corporis 50 (25%) was most common clinical types. KOH mount was positive in 89 (44.5%) and culture was positive in 111 (55.5%). Trichophyton mentagrophytes 44 (39.6%) was the most common isolate. Conclusions. The diagnostic yields of KOH mount and culture were found to be complementary to each other. Thus both the methods added with clinical findings are equally important to establish superficial mycosis. Hindawi Publishing Corporation 2016 2016-11-24 /pmc/articles/PMC5143727/ /pubmed/28003819 http://dx.doi.org/10.1155/2016/9509705 Text en Copyright © 2016 Sundar Khadka et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Khadka, Sundar
Sherchand, Jeevan Bahadur
Pokharel, Dinesh Binod
Pokhrel, Bharat Mani
Mishra, Shyam Kumar
Dhital, Subhash
Rijal, Basista
Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal
title Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal
title_full Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal
title_fullStr Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal
title_full_unstemmed Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal
title_short Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal
title_sort clinicomycological characterization of superficial mycoses from a tertiary care hospital in nepal
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143727/
https://www.ncbi.nlm.nih.gov/pubmed/28003819
http://dx.doi.org/10.1155/2016/9509705
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