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Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review
Patients with advanced chronic kidney disease including ESRD patients may present with a wide spectrum of cutaneous abnormalities, ranging from xerosis to hyperpigmentation to severe deforming necrotizing lesions. Skin problems are not uncommon in this population of patients, with a clinical present...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143733/ https://www.ncbi.nlm.nih.gov/pubmed/28003921 http://dx.doi.org/10.1155/2016/6713807 |
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author | Bhat, Zeenat Yousuf Abu Minshar, Marwan Imran, Nashat Thompson, Andrew Malik, Yahya Osman |
author_facet | Bhat, Zeenat Yousuf Abu Minshar, Marwan Imran, Nashat Thompson, Andrew Malik, Yahya Osman |
author_sort | Bhat, Zeenat Yousuf |
collection | PubMed |
description | Patients with advanced chronic kidney disease including ESRD patients may present with a wide spectrum of cutaneous abnormalities, ranging from xerosis to hyperpigmentation to severe deforming necrotizing lesions. Skin problems are not uncommon in this population of patients, with a clinical presentation that can be quite bizarre, mandating a long list of differential diagnostic possibilities, and subsequent rise of a puzzling diagnostic challenge. We describe an ESRD patient who presented with blistering, nonhealing ulcerative lesions with a diagnostic skin biopsy revealing a mixed pattern of linear IgA bullous dermatosis and dermatitis herpetiformis. A clinical remission could be achieved with pulse intravenous steroids followed by oral maintenance in combination with dapsone, with no evidence of recurrence. |
format | Online Article Text |
id | pubmed-5143733 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-51437332016-12-21 Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review Bhat, Zeenat Yousuf Abu Minshar, Marwan Imran, Nashat Thompson, Andrew Malik, Yahya Osman Case Rep Nephrol Case Report Patients with advanced chronic kidney disease including ESRD patients may present with a wide spectrum of cutaneous abnormalities, ranging from xerosis to hyperpigmentation to severe deforming necrotizing lesions. Skin problems are not uncommon in this population of patients, with a clinical presentation that can be quite bizarre, mandating a long list of differential diagnostic possibilities, and subsequent rise of a puzzling diagnostic challenge. We describe an ESRD patient who presented with blistering, nonhealing ulcerative lesions with a diagnostic skin biopsy revealing a mixed pattern of linear IgA bullous dermatosis and dermatitis herpetiformis. A clinical remission could be achieved with pulse intravenous steroids followed by oral maintenance in combination with dapsone, with no evidence of recurrence. Hindawi Publishing Corporation 2016 2016-11-24 /pmc/articles/PMC5143733/ /pubmed/28003921 http://dx.doi.org/10.1155/2016/6713807 Text en Copyright © 2016 Zeenat Yousuf Bhat et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Bhat, Zeenat Yousuf Abu Minshar, Marwan Imran, Nashat Thompson, Andrew Malik, Yahya Osman Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review |
title | Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review |
title_full | Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review |
title_fullStr | Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review |
title_full_unstemmed | Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review |
title_short | Bullous Dermatosis in an End-Stage Renal Disease Patient: A Case Report and Literature Review |
title_sort | bullous dermatosis in an end-stage renal disease patient: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143733/ https://www.ncbi.nlm.nih.gov/pubmed/28003921 http://dx.doi.org/10.1155/2016/6713807 |
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