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Functional connectivity changes resemble patterns of pTDP-43 pathology in amyotrophic lateral sclerosis

‘Resting-state’ fMRI allows investigation of alterations in functional brain organization that are associated with an underlying pathological process. We determine whether abnormal connectivity in amyotrophic lateral sclerosis (ALS) in a priori-defined intrinsic functional connectivity networks, acc...

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Detalles Bibliográficos
Autores principales: Schulthess, Ines, Gorges, Martin, Müller, Hans-Peter, Lulé, Dorothée, Del Tredici, Kelly, Ludolph, Albert C., Kassubek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144012/
https://www.ncbi.nlm.nih.gov/pubmed/27929102
http://dx.doi.org/10.1038/srep38391