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GSK-3β controls NF-kappaB activity via IKKγ/NEMO

The NF-κB signaling pathway is central for the innate immune response and its deregulation is found in multiple disorders such as autoimmune, chronic inflammatory and metabolic diseases. IKKγ/NEMO is essential for NF-κB activation and NEMO dysfunction in humans has been linked to so-called progeria...

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Detalles Bibliográficos
Autores principales:	Medunjanin, Senad, Schleithoff, Lisa, Fiegehenn, Christian, Weinert, Soenke, Zuschratter, Werner, Braun-Dullaeus, Ruediger C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144080/ https://www.ncbi.nlm.nih.gov/pubmed/27929056 http://dx.doi.org/10.1038/srep38553

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