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Concordance between somatic copy number loss and down-regulated expression: A pan-cancer study of cancer predisposition genes

Cancer predisposition genes (CPGs) are a class of cancer genes in which germline variants lead to increased risk of cancer. Research has revealed that copy number variation (CNV) may be linked to cancer susceptibility in CPGs. In this pan-cancer analysis, we explored the relationship between somatic...

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Detalles Bibliográficos
Autores principales: Wei, Ran, Zhao, Ming, Zheng, Chun-Hou, Zhao, Min, Xia, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144096/
https://www.ncbi.nlm.nih.gov/pubmed/27929028
http://dx.doi.org/10.1038/srep37358