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Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China
Empirical evidence has suggested that social support from family can help patients take their medicines correctly. This study aims to evaluate the role of a family member-based supervision package in the management of hypertension using a cluster randomized trial in rural China. We recruited patient...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144121/ https://www.ncbi.nlm.nih.gov/pubmed/26911532 http://dx.doi.org/10.1038/jhh.2016.8 |
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author | Shen, Y Peng, X Wang, M Zheng, X Xu, G Lü, L Xu, K Burstrom, B Burstrom, K Wang, J |
author_facet | Shen, Y Peng, X Wang, M Zheng, X Xu, G Lü, L Xu, K Burstrom, B Burstrom, K Wang, J |
author_sort | Shen, Y |
collection | PubMed |
description | Empirical evidence has suggested that social support from family can help patients take their medicines correctly. This study aims to evaluate the role of a family member-based supervision package in the management of hypertension using a cluster randomized trial in rural China. We recruited patients with hypertension from four villages in Yangzhong and randomly allocated them to the control group (n=288) and the intervention group (n=266). A family member-based supervision package was applied to the intervention group, while the usual service was applied to the controls. Patients were followed for 12 months and completed face-to-face interviews at the end of 6 and 12 months. The primary outcomes were patients' medication adherence and frequency of blood pressure measurement. Secondary outcomes included changes in blood pressure, altered risk behaviours and occurrence of hypertension-related complications. To control for the effects of cluster randomization, multilevel mixed-effects regression models were used to compare group changes. We observed that the intervention improved patients' blood pressure measurement frequency (OR: 9.00, 95% CI: 4.52–17.91) and adherence to antihypertensive treatment (OR: 1.74, 95% CI: 0.91–3.32). Its effect on the blood pressure control rate was significant at the mid-term investigation (OR: 0.67, 95% CI: 0.40–0.93), but the long-term effect was not significant (OR: 0.89, 95% CI: 0.64–1.26). After 6 months of intervention, either systolic or diastolic blood pressure was significantly decreased in the intervention group. However, this difference was not significant at the final investigation. Findings from this study revealed that the family member-based supervised therapy may have positive effects on patients' adherence to blood monitoring and hypertensive medications. |
format | Online Article Text |
id | pubmed-5144121 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-51441212017-01-13 Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China Shen, Y Peng, X Wang, M Zheng, X Xu, G Lü, L Xu, K Burstrom, B Burstrom, K Wang, J J Hum Hypertens Original Article Empirical evidence has suggested that social support from family can help patients take their medicines correctly. This study aims to evaluate the role of a family member-based supervision package in the management of hypertension using a cluster randomized trial in rural China. We recruited patients with hypertension from four villages in Yangzhong and randomly allocated them to the control group (n=288) and the intervention group (n=266). A family member-based supervision package was applied to the intervention group, while the usual service was applied to the controls. Patients were followed for 12 months and completed face-to-face interviews at the end of 6 and 12 months. The primary outcomes were patients' medication adherence and frequency of blood pressure measurement. Secondary outcomes included changes in blood pressure, altered risk behaviours and occurrence of hypertension-related complications. To control for the effects of cluster randomization, multilevel mixed-effects regression models were used to compare group changes. We observed that the intervention improved patients' blood pressure measurement frequency (OR: 9.00, 95% CI: 4.52–17.91) and adherence to antihypertensive treatment (OR: 1.74, 95% CI: 0.91–3.32). Its effect on the blood pressure control rate was significant at the mid-term investigation (OR: 0.67, 95% CI: 0.40–0.93), but the long-term effect was not significant (OR: 0.89, 95% CI: 0.64–1.26). After 6 months of intervention, either systolic or diastolic blood pressure was significantly decreased in the intervention group. However, this difference was not significant at the final investigation. Findings from this study revealed that the family member-based supervised therapy may have positive effects on patients' adherence to blood monitoring and hypertensive medications. Nature Publishing Group 2017-01 2016-02-25 /pmc/articles/PMC5144121/ /pubmed/26911532 http://dx.doi.org/10.1038/jhh.2016.8 Text en Copyright © 2017 Macmillan Publishers Limited http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Original Article Shen, Y Peng, X Wang, M Zheng, X Xu, G Lü, L Xu, K Burstrom, B Burstrom, K Wang, J Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China |
title | Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China |
title_full | Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China |
title_fullStr | Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China |
title_full_unstemmed | Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China |
title_short | Family member-based supervision of patients with hypertension: a cluster randomized trial in rural China |
title_sort | family member-based supervision of patients with hypertension: a cluster randomized trial in rural china |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144121/ https://www.ncbi.nlm.nih.gov/pubmed/26911532 http://dx.doi.org/10.1038/jhh.2016.8 |
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