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Clinical correlates of leukoaraiosis: A study of 175 patients
BACKGROUND: In India, the correlates of leukoaraiosis (LA) have not been widely reported. This study was designed to investigate the factors which correlate with LA. MATERIALS AND METHODS: We included patients with LA who consented for the study and graded their severity on the basis of Fazekas scal...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144469/ https://www.ncbi.nlm.nih.gov/pubmed/27994357 http://dx.doi.org/10.4103/0972-2327.194425 |
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author | Wadia, Rustom S. Ghiya, Sandesh K. Singh, Joshita Sontakke, Santosh M. Bharadwaj, Vishwas Sonawane, Rahul V. Bade, Yogesh P. Shrikanth, K. Goli, Nikhil Chauhan, Rohit Singh Nadkarni, Nilesh A. |
author_facet | Wadia, Rustom S. Ghiya, Sandesh K. Singh, Joshita Sontakke, Santosh M. Bharadwaj, Vishwas Sonawane, Rahul V. Bade, Yogesh P. Shrikanth, K. Goli, Nikhil Chauhan, Rohit Singh Nadkarni, Nilesh A. |
author_sort | Wadia, Rustom S. |
collection | PubMed |
description | BACKGROUND: In India, the correlates of leukoaraiosis (LA) have not been widely reported. This study was designed to investigate the factors which correlate with LA. MATERIALS AND METHODS: We included patients with LA who consented for the study and graded their severity on the basis of Fazekas scale. We excluded patients with LA who did not consent/cooperate for the study as also patients with other white matter changes which mimic LA. RESULTS: LA is a common and under-rated cause of disability. Presentations include cognitive decline, gait disturbance, dysarthria, bladder/bowel sphincter disturbances, and increased risk of stroke. The comorbidities include hyperhomocysteinemia, hypertension, dyslipidemia, tobacco use, ischemic heart disease, previous stroke, atrial fibrillation, chronic renal failure, and bariatric surgery. |
format | Online Article Text |
id | pubmed-5144469 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-51444692016-12-19 Clinical correlates of leukoaraiosis: A study of 175 patients Wadia, Rustom S. Ghiya, Sandesh K. Singh, Joshita Sontakke, Santosh M. Bharadwaj, Vishwas Sonawane, Rahul V. Bade, Yogesh P. Shrikanth, K. Goli, Nikhil Chauhan, Rohit Singh Nadkarni, Nilesh A. Ann Indian Acad Neurol Original Article BACKGROUND: In India, the correlates of leukoaraiosis (LA) have not been widely reported. This study was designed to investigate the factors which correlate with LA. MATERIALS AND METHODS: We included patients with LA who consented for the study and graded their severity on the basis of Fazekas scale. We excluded patients with LA who did not consent/cooperate for the study as also patients with other white matter changes which mimic LA. RESULTS: LA is a common and under-rated cause of disability. Presentations include cognitive decline, gait disturbance, dysarthria, bladder/bowel sphincter disturbances, and increased risk of stroke. The comorbidities include hyperhomocysteinemia, hypertension, dyslipidemia, tobacco use, ischemic heart disease, previous stroke, atrial fibrillation, chronic renal failure, and bariatric surgery. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5144469/ /pubmed/27994357 http://dx.doi.org/10.4103/0972-2327.194425 Text en Copyright: © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Wadia, Rustom S. Ghiya, Sandesh K. Singh, Joshita Sontakke, Santosh M. Bharadwaj, Vishwas Sonawane, Rahul V. Bade, Yogesh P. Shrikanth, K. Goli, Nikhil Chauhan, Rohit Singh Nadkarni, Nilesh A. Clinical correlates of leukoaraiosis: A study of 175 patients |
title | Clinical correlates of leukoaraiosis: A study of 175 patients |
title_full | Clinical correlates of leukoaraiosis: A study of 175 patients |
title_fullStr | Clinical correlates of leukoaraiosis: A study of 175 patients |
title_full_unstemmed | Clinical correlates of leukoaraiosis: A study of 175 patients |
title_short | Clinical correlates of leukoaraiosis: A study of 175 patients |
title_sort | clinical correlates of leukoaraiosis: a study of 175 patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144469/ https://www.ncbi.nlm.nih.gov/pubmed/27994357 http://dx.doi.org/10.4103/0972-2327.194425 |
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