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Intraoperative Analysis of Flow Dynamics in Arteriovenous Composite Y Grafts

OBJECTIVE: Composite graft of left internal thoracic artery and great saphenous vein in revascularization of the left coronary system is a technique well described in literature. The aim of this study is to analyze blood flow dynamics in this configuration of composite graft especially in what conce...

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Autores principales: Lobo Filho, Heraldo Guedis, Lobo Filho, José Glauco, Pimentel, Matheus Duarte, Silva, Bruno Gadelha Bezerra, de Souza, Camylla Santos, Montenegro, Marília Leitão, Leitão, Maria Cláudia de Azevedo, Jamacuru, Francisco Vagnaldo Fechine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144566/
https://www.ncbi.nlm.nih.gov/pubmed/27982343
http://dx.doi.org/10.5935/1678-9741.20160053
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author Lobo Filho, Heraldo Guedis
Lobo Filho, José Glauco
Pimentel, Matheus Duarte
Silva, Bruno Gadelha Bezerra
de Souza, Camylla Santos
Montenegro, Marília Leitão
Leitão, Maria Cláudia de Azevedo
Jamacuru, Francisco Vagnaldo Fechine
author_facet Lobo Filho, Heraldo Guedis
Lobo Filho, José Glauco
Pimentel, Matheus Duarte
Silva, Bruno Gadelha Bezerra
de Souza, Camylla Santos
Montenegro, Marília Leitão
Leitão, Maria Cláudia de Azevedo
Jamacuru, Francisco Vagnaldo Fechine
author_sort Lobo Filho, Heraldo Guedis
collection PubMed
description OBJECTIVE: Composite graft of left internal thoracic artery and great saphenous vein in revascularization of the left coronary system is a technique well described in literature. The aim of this study is to analyze blood flow dynamics in this configuration of composite graft especially in what concerns left internal thoracic artery's adaptability and influence of great saphenous vein segment on left internal thoracic artery's flow. METHODS: Revascularization of left coronary system with composite graft, with left internal thoracic artery revascularizing the anterior interventricular artery and a great saphenous vein segment, anastomosed to the left internal thoracic artery, revascularizing another branch of the left coronary system, was performed in 23 patients. Blood flow was evaluated by transit time flowmetry in all segments of the composite graft (left internal thoracic artery proximal segment, left internal thoracic artery distal segment and great saphenous vein segment). Measures were performed in baseline condition and after dobutamine-induced stress, without and with non-traumatic temporary clamping of the distal segments of the composite graft. RESULTS: Pharmacological stress resulted in increase of blood flow values in the analyzed segments (P<0.05). Non-traumatic temporary clamping of great saphenous vein segment did not result in statistically significant changes in the flow of left internal thoracic artery distal segment, both in baseline condition and under pharmacological stress. Similarly, non-traumatic temporary clamping of left internal thoracic artery distal segment did not result in statistically significant changes in great saphenous vein segment flow. CONCLUSION: Composite grafts with left internal thoracic artery and great saphenous vein for revascularization of left coronary system, resulted in blood flow dynamics with physiological adaptability, both at rest and after pharmacological stress, according to demand. Presence of great saphenous vein segment did not alter physiological blood flow dynamics in distal segment of left internal thoracic artery.
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spelling pubmed-51445662016-12-09 Intraoperative Analysis of Flow Dynamics in Arteriovenous Composite Y Grafts Lobo Filho, Heraldo Guedis Lobo Filho, José Glauco Pimentel, Matheus Duarte Silva, Bruno Gadelha Bezerra de Souza, Camylla Santos Montenegro, Marília Leitão Leitão, Maria Cláudia de Azevedo Jamacuru, Francisco Vagnaldo Fechine Braz J Cardiovasc Surg Original Articles OBJECTIVE: Composite graft of left internal thoracic artery and great saphenous vein in revascularization of the left coronary system is a technique well described in literature. The aim of this study is to analyze blood flow dynamics in this configuration of composite graft especially in what concerns left internal thoracic artery's adaptability and influence of great saphenous vein segment on left internal thoracic artery's flow. METHODS: Revascularization of left coronary system with composite graft, with left internal thoracic artery revascularizing the anterior interventricular artery and a great saphenous vein segment, anastomosed to the left internal thoracic artery, revascularizing another branch of the left coronary system, was performed in 23 patients. Blood flow was evaluated by transit time flowmetry in all segments of the composite graft (left internal thoracic artery proximal segment, left internal thoracic artery distal segment and great saphenous vein segment). Measures were performed in baseline condition and after dobutamine-induced stress, without and with non-traumatic temporary clamping of the distal segments of the composite graft. RESULTS: Pharmacological stress resulted in increase of blood flow values in the analyzed segments (P<0.05). Non-traumatic temporary clamping of great saphenous vein segment did not result in statistically significant changes in the flow of left internal thoracic artery distal segment, both in baseline condition and under pharmacological stress. Similarly, non-traumatic temporary clamping of left internal thoracic artery distal segment did not result in statistically significant changes in great saphenous vein segment flow. CONCLUSION: Composite grafts with left internal thoracic artery and great saphenous vein for revascularization of left coronary system, resulted in blood flow dynamics with physiological adaptability, both at rest and after pharmacological stress, according to demand. Presence of great saphenous vein segment did not alter physiological blood flow dynamics in distal segment of left internal thoracic artery. Sociedade Brasileira de Cirurgia Cardiovascular 2016 /pmc/articles/PMC5144566/ /pubmed/27982343 http://dx.doi.org/10.5935/1678-9741.20160053 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Lobo Filho, Heraldo Guedis
Lobo Filho, José Glauco
Pimentel, Matheus Duarte
Silva, Bruno Gadelha Bezerra
de Souza, Camylla Santos
Montenegro, Marília Leitão
Leitão, Maria Cláudia de Azevedo
Jamacuru, Francisco Vagnaldo Fechine
Intraoperative Analysis of Flow Dynamics in Arteriovenous Composite Y Grafts
title Intraoperative Analysis of Flow Dynamics in Arteriovenous Composite Y Grafts
title_full Intraoperative Analysis of Flow Dynamics in Arteriovenous Composite Y Grafts
title_fullStr Intraoperative Analysis of Flow Dynamics in Arteriovenous Composite Y Grafts
title_full_unstemmed Intraoperative Analysis of Flow Dynamics in Arteriovenous Composite Y Grafts
title_short Intraoperative Analysis of Flow Dynamics in Arteriovenous Composite Y Grafts
title_sort intraoperative analysis of flow dynamics in arteriovenous composite y grafts
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144566/
https://www.ncbi.nlm.nih.gov/pubmed/27982343
http://dx.doi.org/10.5935/1678-9741.20160053
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